Association of Chlamydia trachomatis Infection and Host Genetic Factors in Manifestation of Reproductive Complications
نویسندگان
چکیده
RTIs including STIs and HIV/AIDS are being increasingly recognised as a serious public health problem. RTIs cause suffering for both men and women, but their consequences are far more devastating and widespread among women. Amongst women, RTIs often go undiagnosed and untreated, and when left untreated, they lead to complications such as infertility, pelvic inflammatory disease, ectopic pregnancy, miscarriage, cervical cancer, and an increased risk of HIV transmission. Adolescents too are vulnerable to RTIs due to their ignorance of risk factors, inadequate accessibility to services, and social powerlessness.
منابع مشابه
P-41: Association Study of MICA*008 Gene Polymorphism with Chlamydia Trachomatis Infection in Infertile Men Reffer to Royan Institute
Background: Chlamydia trachomatis(CT) is an obligate intracellular bacteria, requires living cells to replicate itself. CT infection can remain up to 4 years in the couple and affect their fertility. The relationship between CT and infertility is very important because most patients are asymptomatic and untreated. After infection with CT, NK activation signals begin through interactions of its ...
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Screening for Chlamydia trachomatis among Infertile Women Using PCR Method
Background & objectives: Chlamydia trachomatis is a gram negative bacterium and chlamydia infection, as a curable infection, is one of the most common sexually transmitted diseases (STD). With regard to the essential role of chlamydia in infertility, the study of the prevalence of asymptomatic cases is precious. The aim of this study was to determine of the prevalence of chlamydia trachomatis...
متن کاملThe Prevalence of Chlamydia trachomatis Infection in Women Attending Health Clinics in Shiraz, Islamic Republic of Iran
Background Chlamydia trachomatis (CT) is a common cause of sexually transmitted infections (STI) and a prevalent microorganism found in the vaginal discharge of sexually active women. The infection usually has no symptoms; although it may cause chronic complications such as pelvic inflammatory disease (PID), ectopic pregnancy, chronic pelvic pain, tubal infertility and cervical cancer. This stu...
متن کاملChlamydia trachomatis serovar E isolates from patients with different clinical manifestations have similar courses of infection in a murine model: host factors as major determinants of C trachomatis mediated pathogenesis.
BACKGROUND Some investigators have proposed an association between certain Chlamydia trachomatis serovars and the clinical course of infection in humans. A recent study of over 1100 patients with culture confirmed and serotyped C trachomatis urogenital infection detected no such association. AIMS To corroborate these results using a murine model of female genital tract infection. METHODS Va...
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